Your location: Home > Wiki > Health, Nutrients > Clycine >


Veterinarian Reviewed on January 9, 2012 by Paulina Nelega, RH
Posted in Uncategorized



Clycine is crystalline, colorless, and water-soluble amino acid. It the smallest, simplest, and non-essential amino acid used to help in creating muscle tissue and converting glucose to energy. It helps to maintain healthy digestive and central nervous systems.

Food with high protein such as meat, fish, cheese, beans, and milk are good Clycine dietary sources. It is also available in powder, and capsule forms as well as part of other amino acid supplement combinations.

History and Origin

Clycine was discovered by Henri Braconnot in 1820 through boiling of gelatin with sulfuric acid. It is industrially manufactured by the treatment of chloroacetic acid with ammonia. In the United States and Japan, Clycine is manufactured using the Strecker amino synthesis.

Ancient Uses

Clycine is used in the central nervous system as an inhibitory and excitatory neurotransmitter, specifically in the brainstem, spinal cord and retina.

Clycine is used to help the body construct the regular DNA and RNA strands, the genetic material essential for good cellular formation and function. It helps to avoid muscle breakdown by enhancing the creatine level of the body. Clycine is also found in other connective tissues of the body. The collagen that maintains the skin and its connective tissue to be firm and flexible is one-third part Clycine.

Modern Uses

• Commercial Uses
Clycine is used for pharmaceutical applications including intravenous injections. It is also used for industrial application such as being agent in the metal complexing and finishing.

• Food Uses
It is also an additive in animal feeds and pet foods, while for human related products; it is used for sweetener and taste enhancer. Most food supplements and protein rich drinks have Clycine.

• Personal Care
Clycine works as buffering agent in antiperspirant, analgesic, antacids, and cosmetics.

• General Well-Being
Clycine possesses a calming effect in the brain. It can also promote sound and deeper sleep without morning dizziness. It can also boost agility and memory. Clycine is a glycogenic amino acid that helps in supplying glucose that the body needs for energy. It helps in regulating blood sugar and may be helpful in treating the symptoms characterized by low energy and fatigue including anemia, hypoglycemia, and chronic fatigue syndrome.

• Cancer Treatment
Studies show potential use of Clycine for the treatment of cancer by helping in the prevention of the development of cancerous melanoma and tumors. It helps in keeping healthy prostate. A study shows that it helps reduce prostatic hyperplasia symptoms in men.

Side Effects

People who have liver or kidney disease are discouraged to consume Clycine related products without consultation from their doctor. Having any amino acid supplement may cause disruption of citric acid, and may cause ammonia or nitrogen build up in the body that will lead the kidney and the liver to work harder in removing waste. Anybody who is taking any antispastic drugs must consult their doctor first before using Clycine related product in order to avoid increase in the effects on such medications. It has not exhibit any toxic effect, although some cases reported stomach upset.

Suggested Products

Kalo Ingrown Hair Treatment

Read also: Chuan Xin Lian

Our Expert

Paulina Nelega, RH
Paulina Nelega, RH, has been in private practice as a Clinical Herbalist for over 15 years. She has developed and taught courses in herbal medicine, and her articles on health have appeared in numerous publications. She is very passionate about the healing power of nature. Ask Dr. Jan

Related Posts